Molecular Diagnostic

Gene Express, Inc. formed in 1992 to standardize multi-gene expression measurement and to create reliable molecular diagnostic products. Biomarkers, pharmacogenomics and clinical molecular diagnostics are transforming the practice of medicine with Gene Express' StaRT-PCR™ technology. Major Molecular Diagnostic products have been developed which focus on accurately diagnosing and treating cancer and other diseases. Multi-center clinical testing has begun on the product diagnosing lung cancer.

To address the primary commercial product objective of the Company, Molecular Diagnostic Products, the Gene Express has developed or is developing the following Products:

  • Lung Cancer Products (A battery of four molecular diagnostic products focused on accurately diagnosing and treating lung cancer): Based on a National Cancer Institute grant of $1.2 one of these products, providing a more accurate diagnosis of lung cancer, is in multi-center clinical trials at the New York University Hospital, the Memorial Sloan Kettering Cancer Center, the University of Pittsburgh and the Medical College of Ohio.
  • Bladder Cancer: In cooperative efforts with the University of Southern California, the stages or the disease progression in Bladder Cancer has been identified with StaRT-PCR™ gene expression Indices. This will allow the rapid development of specific tests.
  • Whole Blood Analysis: In a recent study commissioned by Pfizer, Gene Express defined normal ranges of gene transcript values in whole blood. This enables the definition of diseases like Rheumatoid Arthritis, Osteoarthritis, Inflammation, Cardiovascular, Diabetes other diseases to be determined from gene expression measurement in blood.
  • Blood Cultures: Using StaRT-PCR™, we are developing measurement for blood cultures in hours, not days and will identify infection from all 100 bacteria and viruses that attack humans.

Additional information on the Research and Development of Molecular Diagnostic Products at Gene Express Inc. can be seen under Technology at Molecular Diagnostic Product Development
.